Application Closed
The application deadline for this opportunity has passed. You can still review the details, but the listing is no longer presented as open for applications.
PhD & Research, Fellowship
PhD Fellowship in DNA Replication and Early Mammalian Development
Offered by University of Copenhagen – Department of Cellular and Molecular Medicine
Location
Denmark
Funding
Fully Funded
Study level
PhD, Graduates
Field of study
Life Sciences, Natural Sciences, Health & Medical Sciences
Application deadline
October 1, 2026
Application Closed

About This PhD and Research Opportunity
The University of Copenhagen is inviting applications for a fully funded three-year PhD fellowship in DNA Replication and Early Mammalian Development at the Department of Cellular and Molecular Medicine within the Faculty of Health and Medical Sciences.
The PhD position is based in the Halliwell Group and is funded through the Novo Nordisk Foundation Hallas-Møller Emerging Investigator Grant. The successful candidate is expected to commence the position on April 1, 2027, or thereafter.
The research focuses on one of the fundamental questions in developmental biology: how life successfully begins from a single fertilised cell and how the newly formed embryo establishes the molecular machinery required to accurately duplicate its genome.
DNA replication during the earliest stages of mammalian development is still not completely understood. Immediately following fertilisation, the maternal and paternal genomes undergo extensive reprogramming before the embryo begins its first rounds of cell division. During this period, the genome must be accurately duplicated while chromatin organisation and gene-regulatory systems are undergoing major changes.
The PhD project will investigate how DNA replication programmes are established immediately after fertilisation and how these replication processes are coordinated with changes in chromatin organisation and genome regulation.
The research is important because errors in the earliest stages of genome duplication may contribute to embryo arrest, miscarriage, developmental abnormalities and genome instability. Understanding the mechanisms controlling early DNA replication could therefore provide new insights into fundamental developmental processes and reproductive biology.
The project combines several areas of modern biological research, including developmental biology, genome biology, molecular genetics and embryology. The successful candidate will also have opportunities to work with advanced genomic technologies and develop expertise in modern experimental approaches.
The research environment provides access to facilities for human and mouse embryology, advanced microscopy, genome engineering, transgenic mouse models and single-cell genomics. This makes the position particularly suitable for candidates interested in interdisciplinary experimental research at the intersection of molecular biology, genetics and developmental biology.
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